Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL8769747 | 0.91 | MAPT (0.38) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL8012449 | 0.86 | CYP1A2 (0.35) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL8470603 | 0.86 | ALDH1A1 (0.53) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL6455111 | 0.84 | MAPT (0.42) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL27756311 | 0.84 | MAPT (0.42) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL8515537 | 0.84 | MAPT (0.42) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL6682064 | 0.84 | MAPT (0.42) | MAPTCYP1A2CYP2C9HPGDMAPK1 | |
| Trolamine SCHEMBL1054048 | 0.84 | SLC7A5 (0.41) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL1054050 | 0.84 | SLC7A5 (0.41) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL10666656 | 0.83 | SLC29A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113881647-B | Transaminase and application thereof in preparation of optically pure chiral amine | 上海合全药物研发有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116926031-A | Transaminase and application thereof in preparation of optically pure chiral amine | 常州合全药业有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-114317475-A | Transaminase and application thereof in preparation of optically pure chiral amine | 上海合全药物研发有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114277010-A | Transaminase and application thereof in preparation of optically pure chiral amine | 上海合全药物研发有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-113881647-A | Transaminase and application thereof in preparation of optically pure chiral amine | 上海合全药物研发有限公司 | 2022-01-04 | — | — | CN | disclosed |