Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676593 | 0.90 | MAPT (0.53) | MAPTTHRBS1PR1TP53GAA | |
| SCHEMBL28665714 | 0.88 | MAPT (0.64) | MAPTTHRBTP53CCKARGAA | |
| SCHEMBL28667847 | 0.84 | MAPT (0.56) | MAPTTHRBTP53GAALMNA | |
| SCHEMBL28665720 | 0.84 | MAPT (0.54) | MAPTTHRBTP53GAALMNA | |
| SCHEMBL28688233 | 0.83 | S1PR1 (0.56) | MAPTTHRBS1PR1GAANPC1 | |
| SCHEMBL28680258 | 0.82 | MAPT (0.53) | MAPTTHRBS1PR1TP53GAA | |
| SCHEMBL28667773 | 0.80 | MAPT (0.62) | MAPTTHRBTP53GAANPC1 | |
| SCHEMBL28681669 | 0.80 | MAPT (0.56) | MAPTTHRBTP53GAANPC1 | |
| SCHEMBL28665641 | 0.78 | MAPT (0.58) | MAPTTHRBTP53GAANPC1 | |
| SCHEMBL28688168 | 0.78 | MAPT (0.53) | MAPTTHRBS1PR1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658889-B | 1,2, 4-oxadiazole-aryl piperazine compound containing naphthalene ring and preparation method and application thereof | 贵州医科大学 | 2021-12-17 | — | — | CN | disclosed |