Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HEXA | P06865 | 2/20 | 0.41 |
| ▸ | HEXB | P07686 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683129 | 0.99 | PDE10A (0.42) | PDE10AHEXAHEXBALDH1A1NPC1 | |
| SCHEMBL28686300 | 0.99 | PDE10A (0.42) | PDE10AHEXAHEXBALDH1A1NPC1 | |
| SCHEMBL28684146 | 0.97 | PDE10A (0.43) | PDE10AHEXAHEXBALDH1A1NPC1 | |
| SCHEMBL28932829 | 0.96 | PDE10A (0.43) | PDE10AHEXAHEXBALDH1A1NPC1 | |
| SCHEMBL28704956 | 0.96 | PDE10A (0.40) | PDE10AHEXAHEXBALDH1A1NPC1 | |
| SCHEMBL28705784 | 0.85 | PDE10A (0.38) | PDE10AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28693050 | 0.80 | HTR4 (0.48) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL28686296 | 0.79 | TRPV4 (0.47) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL28696297 | 0.79 | HEXA (0.41) | HEXAHEXBALDH1A1KDM4EHPGD | |
| SCHEMBL27825025 | 0.77 | PDE10A (0.53) | PDE10AALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665987-B | Naphthaleneimide-polyamine conjugates, methods of making and uses thereof | 河南大学 | 2022-02-18 | — | — | CN | disclosed |