Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 12/20 | 0.46 |
| ▸ | HTR1A | P08908 | 11/20 | 0.46 |
| ▸ | DRD2 | P14416 | 11/20 | 0.46 |
| ▸ | HTR2A | P28223 | 11/20 | 0.46 |
| ▸ | HTR6 | P50406 | 11/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28693050 | 0.92 | HTR4 (0.48) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL27825026 | 0.88 | TRPV4 (0.48) | TRPV4HTR1APDE10A | |
| SCHEMBL28684146 | 0.80 | PDE10A (0.43) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL28932829 | 0.79 | PDE10A (0.43) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL28684142 | 0.79 | PDE10A (0.43) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL28686300 | 0.79 | PDE10A (0.42) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL28683129 | 0.79 | PDE10A (0.42) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL27825025 | 0.78 | PDE10A (0.53) | PDE10A | |
| SCHEMBL27925658 | 0.78 | NPC1 (0.43) | TRPV4 | |
| SCHEMBL28704956 | 0.77 | PDE10A (0.40) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665987-B | Naphthaleneimide-polyamine conjugates, methods of making and uses thereof | 河南大学 | 2022-02-18 | — | — | CN | disclosed |