Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lindane SCHEMBL28681567 | 1.00 | LMNA (0.46) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL555867 | 1.00 | LMNA (0.46) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL2580519 | 0.96 | LMNA (0.42) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL15641482 | 0.96 | LMNA (0.42) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL1016220 | 0.84 | LMNA (0.39) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL333037 | 0.81 | LMNA (0.36) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL4354321 | 0.81 | LMNA (0.36) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL2579810 | 0.81 | LMNA (0.36) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Phosphoric Acid SCHEMBL1498215 | 0.80 | — | — | |
| Phosphoric Acid SCHEMBL11091827 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115613361-A | Preparation method of nano-silver microcapsule and application of nano-silver microcapsule in protective cloth cover | 山东乐康电子产业研究院有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114032588-A | Pre-plating solution and pre-plating process for cyanide-free alkaline copper plating, electroplating solution and electroplating process | 东莞振顺五金制品有限公司 | 2022-02-11 | — | — | CN | disclosed |