Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lindane SCHEMBL28681567 | 1.00 | LMNA (0.46) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL28684263 | 1.00 | LMNA (0.46) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL2580519 | 0.96 | LMNA (0.42) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL15641482 | 0.96 | LMNA (0.42) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL1016220 | 0.84 | LMNA (0.39) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL333037 | 0.81 | LMNA (0.36) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL4354321 | 0.81 | LMNA (0.36) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL2579810 | 0.81 | LMNA (0.36) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Phosphoric Acid SCHEMBL1498215 | 0.80 | — | — | |
| Phosphoric Acid SCHEMBL11091827 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559780-B2 | Method for efficient catalytic synthesis of PAPS based on constructing ATP regeneration system | JIANGNAN UNIVERSITY (CN) | 2026-02-24 | — | — | US | disclosed |
| US-20240215624-A1 | PROCESSED DAIRY-TYPE FOOD PRODUCTS | BK GIULINI GMBH (DE) | 2024-07-04 | — | — | US | disclosed |
| US-12018296-B2 | Recombinant polymerases with increased phototolerance | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| EP-3989326-B1 | ELECTRODE ASSEMBLY HAVING ENHANCED SAFETY AND LITHIUM SECONDARY BATTERY COMPRISING SAME | LG ENERGY SOLUTION LTD (KR) | 2024-04-03 | — | — | EP | disclosed |
| US-11916207-B2 | Battery cell including sealing tape for accelerating heat conduction | LG ENERGY SOLUTION, LTD. (KR) | 2024-02-27 | — | — | US | disclosed |
| US-11891659-B2 | Recombinant polymerases for incorporation of protein shield nucleotide analogs | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-02-06 | — | — | US | disclosed |
| US-11807904-B2 | FRET-labeled compounds and uses therefor | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| EP-3415641-B1 | METHOD FOR ANALYSIS OF MOLECULES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2023-11-01 | — | — | EP | disclosed |
| EP-4262414-A1 | PROCESSED DAIRY-TYPE FOOD PRODUCTS | BK Giulini GmbH (DE) | 2023-10-25 | — | — | EP | disclosed |
| EP-3675266-B1 | BATTERY CELL IN WHICH GELLED ELECTROLYTE COMPONENT IS INCLUDED IN PORE OF SEPARATOR CONFIGURING ELECTRODE ASSEMBLY | LG ENERGY SOLUTION LTD (KR) | 2023-09-20 | — | — | EP | disclosed |
| WO-2007076057-A2 | POLYMERASES FOR NUCLEOTIDE ANALOGUE INCORPORATION | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070141598-A1 | Nucleotide Compositions and Uses Thereof | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| EP-1790202-A2 | APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES | Pacific Biosciences of California, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20060194232-A1 | Sequencing reaction mixture for use in high-resolution detection of labeled nucleotides or labeled nucleic acid targets | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2006-08-31 | — | — | US | disclosed |
| WO-2006086673-A2 | NUCLEOTIDE COMPOSITIONS AND USES THEREOF | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006044078-A2 | APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060061754-A1 | Arrays of optical confinements and uses thereof | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2006-03-23 | — | — | US | disclosed |
| US-20060061755-A1 | Apparatus and method for analysis of molecules | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2006-03-23 | — | — | US | disclosed |
| US-20060063264-A1 | Apparatus and method for performing nucleic acid analysis | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2006-03-23 | — | — | US | disclosed |
| US-20060062531-A1 | Fabrication of optical confinements | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559780-B2 | Method for efficient catalytic synthesis of PAPS based on constructing ATP regeneration system | PAPSS1, ADSL, ADK | LMNA 4187/4885CYP3A4 1951/4885GABRA1 4134/4885 |
| US-11807904-B2 | FRET-labeled compounds and uses therefor | METTL16, BCDIN3D, GARS1 | LMNA 1976/4885CYP3A4 1824/4885GABRA1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.