Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.70 |
| ▸ | NOD1 | Q9Y239 | 8/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.59 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
| ▸ | NMT2 | O60551 | 1/20 | 0.54 |
| ▸ | NMT1 | P30419 | 1/20 | 0.54 |
| ▸ | GLP1R | P43220 | 5/20 | 0.53 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28785969 | 1.00 | SLC6A5 (0.70) | SLC6A5NOD1FOLH1TLR2NMT2 | |
| SCHEMBL29111716 | 0.95 | SLC6A5 (0.77) | SLC6A5NOD1TLR2NMT2NMT1 | |
| SCHEMBL8929340 | 0.95 | SLC6A5 (0.77) | SLC6A5NOD1TLR2NMT2NMT1 | |
| SCHEMBL28874211 | 0.92 | SLC6A5 (0.69) | SLC6A5NOD1TLR2NMT2NMT1 | |
| SCHEMBL28874215 | 0.92 | SLC6A5 (0.69) | SLC6A5NOD1TLR2NMT2NMT1 | |
| SCHEMBL21800919 | 0.91 | NOD1 (0.73) | SLC6A5NOD1GLP1RPLA2G2C | |
| SCHEMBL1713081 | 0.91 | NOD1 (0.73) | SLC6A5NOD1GLP1RPLA2G2C | |
| SCHEMBL1713262 | 0.91 | NOD1 (0.73) | SLC6A5NOD1GLP1RPLA2G2C | |
| SCHEMBL27800899 | 0.90 | SLC6A5 (0.67) | SLC6A5NOD1TLR2NMT2NMT1 | |
| SCHEMBL28580742 | 0.90 | NOD1 (0.76) | SLC6A5NOD1GLP1RPLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865208-B2 | Vesicle useful for external preparation for skin, and external preparation for skin comprising the vesicle | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-10-21 | — | — | US | disclosed |
| US-20100172964-A1 | VESICLE USEFUL FOR EXTERNAL PREPARATION FOR SKIN, AND EXTERNAL PREPARATION FOR SKIN COMPRISING THE VESICLE | POLA CHEMICAL INDUSTRIES INC. (JP) | 2010-07-08 | — | — | US | disclosed |
| EP-2165694-A1 | VESICLE USEFUL FOR EXTERNAL PREPARATION FOR SKIN, AND EXTERNAL PREPARATION FOR SKIN COMPRISING THE VESICLE | Pola Chemical Industries Inc. (JP) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008072717-A1 | METHOD OF EVALUATING SKIN BARRIER FUNCTION, METHOD OF SCREENING MATERIAL FOR ENHANCING SKIN BARRIER FUNCTION USING THE EVALUATING METHOD, THE MATERIAL FOR ENHANCING SKIN BARRIER FUNCTION, AND COSMETIC CONTAINING THE MATERIAL FOR ENHANCING SKIN BARRIER FUNCTION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100172964-A1 | VESICLE USEFUL FOR EXTERNAL PREPARATION FOR SKIN, AND EXTERNAL PREPARATION FOR SKIN COMPRISING THE VESICLE | DEGS1, SGMS2, CERT1 | SLC6A5 2506/4885NOD1 2706/4885FOLH1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.