Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CTSV | O60911 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932143 | 0.87 | CA12 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2PGR | |
| SCHEMBL7650431 | 0.86 | KDM4E (0.65) | KDM4ECA12CA9MEN1KMT2A | |
| SCHEMBL10745767 | 0.83 | CA12 (0.61) | ALDH1A1SMN1; SMN2PGRCA12CA9 | |
| SCHEMBL17434518 | 0.83 | CA12 (0.64) | ALDH1A1CA12CA9MEN1KMT2A | |
| SCHEMBL28694312 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| SCHEMBL29428154 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| SCHEMBL28683072 | 0.81 | MEN1 (0.58) | ALDH1A1HPGDPGRMEN1KMT2A | |
| SCHEMBL28700145 | 0.79 | VCAM1 (0.47) | ALDH1A1SMN1; SMN2CA12CA9MEN1 | |
| SCHEMBL28932333 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDSMN1; SMN2PGR | |
| SCHEMBL10085009 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1HPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776434-B | 3-benzyl-6-acylamino-2, 4- (1H,3H) -quinazoline diketone derivative and synthesis method and application thereof | 中南大学 | 2022-01-28 | — | — | CN | disclosed |