Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28692022 | 0.87 | SETD7 (0.64) | MEN1KMT2APKML3MBTL1MAPT | |
| SCHEMBL29428168 | 0.87 | SETD7 (0.64) | MEN1KMT2APKML3MBTL1MAPT | |
| SCHEMBL28688249 | 0.85 | ALDH1A1 (0.58) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL28684283 | 0.81 | KDM4E (0.62) | MEN1KMT2APGRHPGDALDH1A1 | |
| SCHEMBL2611397 | 0.74 | KDM4E (0.59) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL28683077 | 0.74 | MAPT (0.57) | MEN1KMT2AMAPTPOLBCASP3 | |
| SCHEMBL28685041 | 0.74 | HDAC1 (0.49) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL28932143 | 0.74 | CA12 (0.51) | MEN1KMT2APKMMAPTLMNA | |
| SCHEMBL29428151 | 0.73 | MAPT (0.54) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL6243893 | 0.73 | MAPT (0.71) | MAPTLMNAPOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776434-B | 3-benzyl-6-acylamino-2, 4- (1H,3H) -quinazoline diketone derivative and synthesis method and application thereof | 中南大学 | 2022-01-28 | — | — | CN | disclosed |