Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576713 | 0.83 | PTPN1 (0.40) | PTPN1PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL22774034 | 0.83 | PTPN1 (0.40) | PTPN1PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL22774092 | 0.80 | MAP3K5 (0.34) | PIK3CG | |
| SCHEMBL29576915 | 0.78 | ALDH1A1 (0.40) | PIK3CDPIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL22774058 | 0.78 | ALDH1A1 (0.40) | PIK3CDPIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL5908567 | 0.77 | ALDH1A1 (0.43) | PIK3CDPIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL29576548 | 0.77 | ALDH1A1 (0.43) | PIK3CDPIK3R1PIK3CAPIK3CGMAPT | |
| SCHEMBL30906935 | 0.77 | KDM4E (0.59) | PTGDR2PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL3815099 | 0.77 | KDM4E (0.59) | PTGDR2PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL9860410 | 0.77 | KDM1A (0.42) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113950473-A | Next generation modulators of interferon gene Stimulators (STING) | 雷沃医疗有限公司 | 2022-01-18 | — | — | CN | disclosed |