SCHEMBL9860410

SCHEMBL9860410

N#Cc1cn(C2CC2)c2cc(Cl)ccc2c1=O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 11/20 0.42
XDH P47989 3/20 0.39
MAT2A P31153 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860642 0.79 KDM1A (0.43) KDM1A
SCHEMBL5777474 0.78 KDM1A (0.43) KDM1AXDH
SCHEMBL28684693 0.77 PTPN1 (0.40) MAT2A
SCHEMBL3815099 0.76 KDM4E (0.59)
SCHEMBL30906935 0.76 KDM4E (0.59)
SCHEMBL10586149 0.74 TOP2A (0.35) KDM1AXDH
SCHEMBL9416420 0.73 PIK3CD (0.42) MAT2A
SCHEMBL30906940 0.72 MAT2A (0.45) MAT2A
SCHEMBL10668836 0.72 MAT2A (0.45) MAT2A
SCHEMBL1298234 0.71 KDM1A (0.41) KDM1AXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4782156-A Nitriles of halogenated quinolonecarboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 1988-11-01 US claimed
US-4990646-A Preparation of halogenated quinolonecarboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
US-4956465-A Bactericides BAYER AKTIENGESELLSCHAFT (DE) 1990-09-11 US disclosed
US-4914228-A Preparation of halogenated quinolonecarboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 1990-04-03 US disclosed
US-4782156-A Nitriles of halogenated quinolonecarboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 1988-11-01 US disclosed
US-4680401-A Preparation of halogenated quinolonecarboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 1987-07-14 US disclosed