Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863694 | 0.76 | TSHR (0.50) | — | |
| SCHEMBL27038186 | 0.73 | LMNA (0.53) | — | |
| SCHEMBL8212527 | 0.70 | TSHR (0.52) | TMEM97SIGMAR1TAAR1 | |
| SCHEMBL22732111 | 0.69 | FFAR4 (0.33) | FFAR4 | |
| SCHEMBL22717266 | 0.68 | SMYD2 (0.37) | FFAR4 | |
| SCHEMBL27214476 | 0.67 | NPC1 (0.48) | TAAR1 | |
| SCHEMBL28032871 | 0.66 | TDP1 (0.55) | — | |
| SCHEMBL29060525 | 0.66 | TSHR (0.39) | TAAR1 | |
| SCHEMBL21753894 | 0.66 | IDO1 (0.53) | — | |
| SCHEMBL28690743 | 0.66 | NAAA (0.34) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127062-A | Thiadiazolyl derivatives as inhibitors of DNA polymerase Theta | 伊迪亚生物科学有限公司 | 2022-03-01 | — | — | CN | disclosed |