SCHEMBL863694

SCHEMBL863694

c1ccc(CO[SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
IDO1 P14902 1/20 0.46
AGXT P21549 1/20 0.44
ALDH1A1 P00352 3/20 0.43
PDPK1 O15530 1/20 0.40
MTOR P42345 1/20 0.40
CA1 P00915 3/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
PTGS1 P23219 1/20 0.39
CYP2C19 P33261 1/20 0.39
PTGS2 P35354 1/20 0.39
HIF1A Q16665 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930745 0.84 LTA4H (0.46) TSHRSLC6A2SLC6A3LMNACYP1A2
SCHEMBL18297949 0.81 TSHR (0.50) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL21753894 0.78 IDO1 (0.53) IDO1ALDH1A1LMNACYP1A2CYP2C19
SCHEMBL18297944 0.77 TSHR (0.46) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL4454040 0.77 CA1 (0.42) IDO1ALDH1A1CA1CA2CA9
SCHEMBL2959136 0.77 TSHR (0.57) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL28685236 0.76 TMEM97 (0.34)
SCHEMBL23701189 0.73
SCHEMBL106501 0.73 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL675683 0.73 LTA4H (0.37) TSHRALDH1A1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137525-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2010-06-03 US claimed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US claimed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US claimed
EP-4056604-B1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE KURARAY CO (JP) 2023-08-02 EP disclosed
EP-3564280-B1 COPOLYMER OF 1, 3, 7-OCTATRIENE AND STYRENE AND HYDRIDE THEREOF KURARAY CO (JP) 2023-07-26 EP disclosed
EP-4163312-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-4163311-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-3564274-B1 1, 3, 7-OCTATRIENE POLYMER, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID POLYMER KURARAY CO (JP) 2022-12-28 EP disclosed
EP-4056604-A1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE Kuraray Co., Ltd. (JP) 2022-09-14 EP disclosed
US-11332567-B2 Copolymer of 1, 3, 7-octatriene and butadiene, hydride thereof, and method for producing said copolymer KURARAY CO., LTD. (JP) 2022-05-17 US disclosed
US-11198744-B2 1,3, 7-octatriene polymer, hydride thereof, and method for producing said polymer KURARAY CO., LTD. (JP) 2021-12-14 US disclosed
US-20110086978-A1 Apparatus for hydrogenation and method for hydrogenating conjugated diene polymer by employing the apparatus CHI-MEI CORPORATION 2011-04-14 US disclosed
US-20100137525-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2010-06-03 US disclosed
CN-101698154-A Hydrogenation catalyst composition and use thereof for hydrogenation of conjugated diene polymer CHI MEI CORP 2010-04-28 CN disclosed
US-20080262161-A1 Apparatus for hydrogenation and method for hydrogenating conjugated diene polymer by employing the apparatus CHI-MEI CORPORATION 2008-10-23 US disclosed
CN-101249457-A Hydrogenation catalyst composition and use thereof for hydrogenation of conjugated diene polymer CHI MEI IND CO LTD (CN) 2008-08-27 CN disclosed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US disclosed
CN-1296374-C Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2007-01-24 CN disclosed
CN-1837221-A Production processes for triorganomonochlorosilanes HOKKO CHEM IND CO (JP) 2006-09-27 CN disclosed
CN-1612886-A Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2005-05-04 CN disclosed