Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | CIT | O14578 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359797 | 0.85 | PSMB8 (0.44) | CYP1A2CDC7CITPIM1CSNK2A2 | |
| SCHEMBL28686943 | 0.83 | MPO (0.60) | CYP1A2CDC7CITPIM1CSNK2A2 | |
| SCHEMBL28901276 | 0.80 | CHRNB2 (0.54) | CYP1A2CHRNB2CHRNA4LMNACYP2C19 | |
| SCHEMBL28901281 | 0.80 | CHRNB2 (0.54) | CYP1A2CHRNB2CHRNA4LMNACYP2C19 | |
| SCHEMBL12649101 | 0.80 | CHRNB2 (0.54) | CYP1A2CHRNB2CHRNA4LMNACYP2C19 | |
| SCHEMBL14555059 | 0.78 | MPO (0.61) | CYP1A2CDC7PIM1CSNK2BCSNK2A1 | |
| SCHEMBL29688673 | 0.77 | MPO (0.59) | CYP1A2PSMB8LMNAMAPTTHRB | |
| SCHEMBL4712528 | 0.77 | MPO (0.59) | CYP1A2PSMB8LMNAMAPTTHRB | |
| SCHEMBL7850149 | 0.76 | CHRNB2 (0.60) | CYP1A2CDC7CITPIM1CSNK2A2 | |
| SCHEMBL7842435 | 0.76 | CHRNB2 (0.60) | CYP1A2CDC7CITPIM1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876479-B | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112876478-B | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112876480-B | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112876481-B | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112876477-B | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-109988169-B | Octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-112876480-A | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-112876478-A | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-112876481-A | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-112876475-A | Salts of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-112876477-A | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-112876479-A | Crystalline forms of octahydropyrrolo [3,4-c ] pyrrole derivatives | 广东东阳光药业有限公司 | 2021-06-01 | — | — | CN | disclosed |