SCHEMBL28686121

SCHEMBL28686121

CCCc1nc(Cl)nc(C(C)(C)C)n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27573938 0.83 PDE4A (0.32) LMNAKMT2APDE4A
SCHEMBL10908838 0.80 LMNA (0.42) LMNAKMT2A
SCHEMBL1317963 0.80 ALDH1A1 (0.44) LMNAKMT2A
SCHEMBL1319210 0.75 ALDH1A1 (0.50) LMNAPDE4A
SCHEMBL10874600 0.75 ALDH1A1 (0.41) LMNAPDE4A
SCHEMBL17576118 0.74 LMNA (0.38) LMNA
SCHEMBL19295104 0.71 PDE4A (0.35) LMNAKMT2APDE4A
SCHEMBL9619169 0.71 HRH4 (0.46) LMNAKMT2A
SCHEMBL10810057 0.71 LMNA (0.67) LMNAKMT2APDE4A
SCHEMBL81829 0.70 KDM4E (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113173889-B Method for synthesizing 1,3, 5-triazine derivative 新乡市润宇新材料科技有限公司 2023-11-10 CN disclosed
CN-113173889-A Method for synthesizing 1,3, 5-triazine derivative 新乡市润宇新材料科技有限公司 2021-07-27 CN disclosed