SCHEMBL1319210

SCHEMBL1319210

CC(C)(C)c1nc(Cl)nc(Cl)n1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PDE4A P27815 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10874600 0.94 ALDH1A1 (0.41) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL20502388 0.82 HRH4 (0.43) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL27573938 0.78 PDE4A (0.32) LMNASMN1; SMN2PDE4A
SCHEMBL19295104 0.78 PDE4A (0.35) LMNASMN1; SMN2PDE4A
SCHEMBL28686121 0.75 LMNA (0.33) LMNAPDE4A
SCHEMBL15720180 0.75 ALDH1A1 (0.42) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL376361 0.73 CYP1A2 (0.31) CYP1A2
SCHEMBL14602892 0.71
SCHEMBL7195373 0.71 ALDH1A1 (0.38) ALDH1A1ALOX15TSHRLMNASMN1; SMN2
SCHEMBL1350091 0.71 LMNA (0.30) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260052903-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-02-19 US disclosed
US-11759528-B2 Peg linker and ligand drug conjugate JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2023-09-19 US disclosed
CN-116390928-A Organic electroluminescent element, organic EL display device, and organic EL illumination 三菱化学株式会社 2023-07-04 CN disclosed
US-20230002428-A1 Iridium Complex Compound, Iridium-Complex-Compound-Containing Composition, Organic Electroluminescent Element and Method for Producing Same, Organic EL Display Device, and Organic EL Illuminator MITSUBISHI CHEMICAL CORPORATION (JP) 2023-01-05 US disclosed
US-20230002428-A1 Iridium Complex Compound, Iridium-Complex-Compound-Containing Composition, Organic Electroluminescent Element and Method for Producing Same, Organic EL Display Device, and Organic EL Illuminator MITSUBISHI CHEMICAL CORPORATION (JP) 2023-01-05 US disclosed
EP-4105222-A1 IRIDIUM COMPLEX COMPOUND, IRIDIUM COMPLEX COMPOUND-CONTAINING COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT AND PRODUCTION METHOD THEREFOR, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL LIGHTING DEVICE Mitsubishi Chemical Corporation (JP) 2022-12-21 EP disclosed
CN-115135662-A Iridium complex compound, composition containing iridium complex compound, organic electroluminescent element and method for producing same, organic EL display device, and organic EL lighting device 三菱化学株式会社 2022-09-30 CN disclosed
WO-2022115039-A1 MAGNETIC NANOCOMPOSITE MATERIALS SUITABLE FOR MAGNETIC LOCALIZED POLYMERISATION OF AN ANAEROBIC ADHESIVE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-06-02 WO disclosed
WO-2022092046-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL LIGHTING 三菱ケミカル株式会社 2022-05-05 WO disclosed
WO-2021161974-A1 IRIDIUM COMPLEX COMPOUND, IRIDIUM COMPLEX COMPOUND-CONTAINING COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT AND PRODUCTION METHOD THEREFOR, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL LIGHTING DEVICE 三菱ケミカル株式会社 2021-08-19 WO disclosed
US-8003645-B2 type II diabetes; 6-Ethyl-N,N'-bis(3-hydroxyphenyl)-1,3,5-triazine-2,4-diamine; suppress the fall in MTT reduction capacity by beta -amyloid protein; inhibit impairment of long-term potentiation of hippocampal nerve cells, pyrimidine or 1,3,5 triazine derivatives BTG INTERNATIONAL LTD. (GB) 2011-08-23 US disclosed
US-20090286794-A1 Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound BTG INTERNATIONAL LTD. (GB) 2009-11-19 US disclosed
US-20090286809-A1 Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound BTG INTERNATIONAL LTD. (GB) 2009-11-19 US disclosed
US-7589105-B2 For example, N,N'-bis(3-hydroxyphenyl)pyrimidine-4,6-diamine, 2-methyl-N,N'-bis(3-hydroxyphenyl)pyrimidine-4,6-diamine BTG INTERNATIONAL LIMITED (GB) 2009-09-15 US disclosed
EP-1473289-B1 PREVENTIVES OR REMEDIES FOR ALZHEIMER'S DISEASE OR AMYLOID PROTEIN FIBROSIS INHIBITORS CONTAINING NITROGEN-CONTAINING HETEROARYL COMPOUNDS BTG INT LTD (GB) 2009-08-05 EP disclosed
US-20080182846-A1 Preventives or remedies for Alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound BTG INTERNATIONAL LIMITED (GB) 2008-07-31 US disclosed
US-20050054732-A1 Preventives or remidies for alzheimer's disease or amyloid protein fibrosis inhibitors containing nitrogen-containing heteroaryl compounds BTG INTERNATIONAL LTD. (GB) 2005-03-10 US disclosed
EP-1473289-A1 PREVENTIVES OR REMEDIES FOR ALZHEIMER'S DISEASE OR AMYLOID PROTEIN FIBROSIS INHIBITORS CONTAINING NITROGEN-CONTAINING HETEROARYL COMPOUNDS Sankyo Company, Limited (JP) 2004-11-03 EP disclosed
US-4659820-A Process for the preparation of 4-alkoxy-6-alkyl-2-cyanamino-1,3,5-triazines BAYER AKTIENGESELLSCHAFT (DE) 1987-04-21 US disclosed
US-4211688-A Process for dyeing high-molecular organic material in the melt CIBA-GEIGY CORPORATION (US) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054732-A1 Preventives or remidies for alzheimer's disease or amyloid protein fibrosis inhibitors containing nitrogen-containing heteroaryl compounds NAT1, APP, BACE1 ALDH1A1 1310/4885ALOX15 350/4885TSHR 3007/4885
US-20230002428-A1 Iridium Complex Compound, Iridium-Complex-Compound-Containing Composition, Organic Electroluminescent Element and Method for Producing Same, Organic EL Display Device, and Organic EL Illuminator INF2, EMC2, DRD4 ALDH1A1 989/4885ALOX15 1656/4885TSHR 1733/4885
US-20260052903-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE EMC1, CRY1, CBR1 ALDH1A1 174/4885ALOX15 1169/4885TSHR 1209/4885
US-20090286794-A1 Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound APP, BACE1, PSEN1 ALDH1A1 2328/4885ALOX15 447/4885TSHR 3082/4885
US-11759528-B2 Peg linker and ligand drug conjugate EGFR, MPEG1, ERBB2 ALDH1A1 1675/4885ALOX15 3964/4885TSHR 225/4885
US-20090286809-A1 Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound APP, BACE1, PSEN1 ALDH1A1 2328/4885ALOX15 447/4885TSHR 3082/4885
US-20080182846-A1 Preventives or remedies for Alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound APP, BACE1, PSEN1 ALDH1A1 2328/4885ALOX15 447/4885TSHR 3082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.