Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22409141 | 0.86 | POLB (0.49) | ALDH1A1LMNATSHRRXRARXRB | |
| SCHEMBL29401375 | 0.86 | POLB (0.49) | ALDH1A1LMNATSHRRXRARXRB | |
| SCHEMBL29401495 | 0.81 | EDNRB (0.40) | ALDH1A1LMNACA1CA2TSHR | |
| SCHEMBL977122 | 0.81 | EDNRB (0.40) | ALDH1A1LMNACA1CA2TSHR | |
| SCHEMBL22409170 | 0.80 | EDNRB (0.41) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL29405486 | 0.80 | EDNRB (0.41) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL22409055 | 0.79 | EDNRB (0.40) | ALDH1A1LMNACA1CA2MEN1 | |
| SCHEMBL29404286 | 0.79 | EDNRB (0.40) | ALDH1A1LMNACA1CA2MEN1 | |
| SCHEMBL22409153 | 0.78 | PTPN1 (0.43) | ALDH1A1CA1CA2KMT2AMAPT | |
| SCHEMBL30884146 | 0.78 | PTPN1 (0.43) | ALDH1A1CA1CA2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072390-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2022-02-18 | — | — | CN | disclosed |