Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22409055 | 1.00 | EDNRB (0.40) | EDNRBEDNRANSD2MAPTSMN1; SMN2 | |
| SCHEMBL29405486 | 0.86 | EDNRB (0.41) | EDNRBEDNRANSD2MAPTSMN1; SMN2 | |
| SCHEMBL22409170 | 0.86 | EDNRB (0.41) | EDNRBEDNRANSD2MAPTSMN1; SMN2 | |
| SCHEMBL977122 | 0.84 | EDNRB (0.40) | EDNRBEDNRANSD2MAPTSMN1; SMN2 | |
| SCHEMBL29401495 | 0.84 | EDNRB (0.40) | EDNRBEDNRANSD2MAPTSMN1; SMN2 | |
| SCHEMBL1793262 | 0.81 | ALOX5AP (0.40) | NSD2MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL22409141 | 0.81 | POLB (0.49) | EDNRBEDNRAMAPTKDM4ELMNA | |
| SCHEMBL29401375 | 0.81 | POLB (0.49) | EDNRBEDNRAMAPTKDM4ELMNA | |
| SCHEMBL1793056 | 0.79 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20807647 | 0.79 | NSD2 (0.45) | NSD2MAPTSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072390-B | RAD51 inhibitors | 赛泰尔治疗公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114072390-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2022-02-18 | — | — | CN | disclosed |