Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22409141 | 1.00 | POLB (0.49) | POLBCYP26A1MEP1BHTTMEN1 | |
| SCHEMBL28686223 | 0.86 | ALDH1A1 (0.45) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL22409152 | 0.86 | ALDH1A1 (0.43) | POLBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL977122 | 0.84 | EDNRB (0.40) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL29401495 | 0.84 | EDNRB (0.40) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL22409224 | 0.83 | POLB (0.49) | POLBMEP1BHTTMEN1KMT2A | |
| SCHEMBL29403823 | 0.83 | POLB (0.49) | POLBMEP1BHTTMEN1KMT2A | |
| SCHEMBL22409178 | 0.83 | KMT2A (0.41) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL29403331 | 0.83 | KMT2A (0.41) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL30884143 | 0.82 | L3MBTL1 (0.53) | MEN1KMT2AMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072390-B | RAD51 inhibitors | 赛泰尔治疗公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114072390-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2022-02-18 | — | — | CN | disclosed |