Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977122 | 1.00 | EDNRB (0.40) | EDNRBEDNRARAB9ALMNAMEN1 | |
| SCHEMBL29405486 | 0.86 | EDNRB (0.41) | EDNRBEDNRARAB9ALMNAMEN1 | |
| SCHEMBL22409170 | 0.86 | EDNRB (0.41) | EDNRBEDNRARAB9ALMNAMEN1 | |
| SCHEMBL22409055 | 0.84 | EDNRB (0.40) | EDNRBEDNRARAB9ALMNAMEN1 | |
| SCHEMBL29404286 | 0.84 | EDNRB (0.40) | EDNRBEDNRARAB9ALMNAMEN1 | |
| SCHEMBL22409141 | 0.84 | POLB (0.49) | EDNRBEDNRALMNAMEN1KMT2A | |
| SCHEMBL29401375 | 0.84 | POLB (0.49) | EDNRBEDNRALMNAMEN1KMT2A | |
| SCHEMBL22409153 | 0.81 | PTPN1 (0.43) | RAB9AKMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL30884146 | 0.81 | PTPN1 (0.43) | RAB9AKMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL22409152 | 0.81 | ALDH1A1 (0.43) | EDNRBEDNRARAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072390-B | RAD51 inhibitors | 赛泰尔治疗公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114072390-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2022-02-18 | — | — | CN | disclosed |