Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744803 | 0.77 | ALDH1A1 (0.45) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL17809620 | 0.72 | ALDH1A1 (0.51) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL22144473 | 0.70 | ALDH1A1 (0.49) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL17809574 | 0.70 | ALDH1A1 (0.51) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL17809611 | 0.69 | MEN1 (0.50) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL16573987 | 0.69 | CA12 (0.73) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17795410 | 0.68 | CREBBP (0.54) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4552802 | 0.67 | CA12 (0.57) | HPGDMEN1KMT2ACA12CA9 | |
| SCHEMBL17809777 | 0.67 | CYP11B2 (0.48) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL10647052 | 0.67 | WDR5 (0.41) | HPGDMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811529-A | Fibroblast activation protein inhibitor | 普拉西斯生物技术有限责任公司 | 2021-12-17 | — | — | CN | disclosed |