Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050408 | 0.81 | LMNA (0.52) | SMN1; SMN2KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL16756573 | 0.81 | LMNA (0.54) | SMN1; SMN2KMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL432494 | 0.81 | NPC1 (0.52) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL26045534 | 0.80 | TSHR (0.48) | SMN1; SMN2KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL11525638 | 0.80 | KMT2A (0.52) | SMN1; SMN2KMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL8699954 | 0.80 | KMT2A (0.48) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL11554391 | 0.79 | NPC1 (0.49) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5678485 | 0.79 | LMNA (0.53) | SMN1; SMN2KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL16989810 | 0.78 | RIPK1 (0.46) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28146646 | 0.77 | RIPK1 (0.49) | SMN1; SMN2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024326-A | 5-amino substituted indole compound, preparation method thereof and application thereof in anti-acetylcholinesterase medicine | 平顶山学院 | 2023-11-10 | — | — | CN | disclosed |
| CN-114213272-B | Synthetic method of arylethynyl formamide compound | 江南大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-114213272-A | Synthetic method of arylethynyl formamide compound | 江南大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-110357832-B | Preparation method of aromatic amine compound, EphB4 kinase inhibitor and derivatives thereof | 武汉大学 | 2022-03-15 | — | — | CN | disclosed |