Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143661 | 0.80 | ROCK1 (0.55) | LIPGROCK1FFAR1FFAR4POLB | |
| SCHEMBL25241808 | 0.80 | ROCK1 (0.37) | LIPGROCK1CXCR2 | |
| SCHEMBL17165827 | 0.79 | ROCK1 (0.36) | LIPGROCK1CXCR2 | |
| SCHEMBL31254711 | 0.79 | ROCK1 (0.36) | LIPGROCK1CXCR2 | |
| SCHEMBL17525546 | 0.79 | ROCK1 (0.38) | LIPGROCK1CXCR2 | |
| SCHEMBL22527705 | 0.77 | ROCK1 (0.39) | ROCK1CXCR2 | |
| SCHEMBL29535058 | 0.77 | ROCK1 (0.39) | ROCK1CXCR2 | |
| SCHEMBL1646761 | 0.76 | LPL (0.44) | LIPGROCK1 | |
| SCHEMBL22748403 | 0.76 | LIPG (0.48) | LIPGROCK1 | |
| SCHEMBL902458 | 0.75 | LIPG (0.49) | LIPGNPSR1FFAR1POLBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113853371-A | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2021-12-28 | — | — | CN | disclosed |