Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079249 | 0.77 | PSMB8 (0.58) | PSMB8PSMB5CA2CA12CA1 | |
| SCHEMBL2206145 | 0.77 | PSMB8 (0.58) | PSMB8PSMB5CA2CA12CA1 | |
| SCHEMBL10474248 | 0.76 | PSMB8 (0.57) | PSMB8PSMB5CA2CA12CA1 | |
| SCHEMBL329578 | 0.75 | PSMB8 (0.70) | PSMB8PSMB5CA2CA12CA1 | |
| SCHEMBL31463118 | 0.75 | PSMB8 (0.70) | PSMB8PSMB5CA2CA12CA1 | |
| SCHEMBL2754297 | 0.75 | PSMB8 (0.70) | PSMB8PSMB5CA2CA12CA1 | |
| SCHEMBL2711265 | 0.75 | PSMB8 (0.75) | PSMB8PSMB5CA2CA12CA1 | |
| Chloromethane SCHEMBL10451709 | 0.74 | PSMB8 (0.64) | PSMB8PSMB5CA2CA12CA1 | |
| SCHEMBL11782652 | 0.74 | PSMB8 (0.68) | PSMB8PSMB5CA2CA12CA1 | |
| Hydrogen Sulfide SCHEMBL27801568 | 0.74 | PSMB8 (0.68) | PSMB8PSMB5CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948039-B | Intermediates and methods for the synthesis of halichondrin B analogs | 卫材R&D管理有限公司 | 2021-12-31 | — | — | CN | disclosed |