Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | MMP2 | P08253 | 12/20 | 0.62 |
| ▸ | MMP9 | P14780 | 10/20 | 0.62 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 4/20 | 0.57 |
| ▸ | MMP13 | P45452 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP7 | P09237 | 3/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690184 | 1.00 | TDP1 (0.72) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL7984346 | 0.88 | TDP1 (0.56) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL18049268 | 0.86 | MMP2 (0.61) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL19923004 | 0.86 | MMP2 (0.61) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL8445799 | 0.85 | MMP2 (0.86) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL4522161 | 0.85 | TDP1 (0.79) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL6252463 | 0.85 | TDP1 (0.79) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL8063645 | 0.84 | TDP1 (0.78) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL697476 | 0.84 | MMP2 (0.79) | TDP1MMP2MMP9ADAMTS4MMP3 | |
| SCHEMBL697477 | 0.84 | MMP2 (0.79) | TDP1MMP2MMP9ADAMTS4MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085911-B | Method for detecting tumor cells or tumor cell fragments | 珠海圣美生物诊断技术有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-114457159-A | Method for detecting tumor cells or tumor cell fragments | 珠海圣美生物诊断技术有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114085911-A | Method for detecting tumor cells or tumor cell fragments | 珠海圣美生物诊断技术有限公司 | 2022-02-25 | — | — | CN | claimed |