Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 6/20 | 0.50 |
| ▸ | MMP2 | P08253 | 6/20 | 0.50 |
| ▸ | MMP13 | P45452 | 5/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP7 | P09237 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | EEF2K | O00418 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981740 | 0.89 | MMP2 (0.56) | CTSLMMP9MMP2MMP13ADAMTS4 | |
| SCHEMBL28690186 | 0.88 | TDP1 (0.72) | TDP1MMP9MMP2MMP13ADAMTS4 | |
| SCHEMBL28690184 | 0.88 | TDP1 (0.72) | TDP1MMP9MMP2MMP13ADAMTS4 | |
| SCHEMBL29682731 | 0.87 | PLAU (0.53) | TDP1CTSLMMP9MMP2MMP13 | |
| SCHEMBL7981960 | 0.85 | TDP1 (0.60) | TDP1CTSLMMP9MMP2ADAMTS4 | |
| SCHEMBL1504320 | 0.84 | TDP1 (0.59) | TDP1CTSLMMP9MMP2POLB | |
| SCHEMBL14534184 | 0.84 | CTSL (0.67) | TDP1CTSLMMP9MMP2ADAMTS4 | |
| SCHEMBL20335146 | 0.84 | CTSL (0.67) | TDP1CTSLMMP9MMP2ADAMTS4 | |
| SCHEMBL8057955 | 0.84 | TDP1 (0.62) | TDP1CTSLMMP9MMP2ADAMTS4 | |
| SCHEMBL20335144 | 0.84 | CTSL (0.67) | TDP1CTSLMMP9MMP2ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |