Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627511 | 0.80 | SLC6A4 (0.46) | SLC6A4HTR6IDO1MAP3K14HTR1A | |
| SCHEMBL28099154 | 0.76 | SLC6A4 (0.46) | SLC6A4HTR6IDO1MAP3K14HTR1A | |
| SCHEMBL13323651 | 0.73 | HTR6 (0.63) | SLC6A4HTR6IDO1MAP3K14HTR1A | |
| SCHEMBL28780556 | 0.72 | MAPK1 (0.46) | HTR6HTR1BHTR2A | |
| SCHEMBL733659 | 0.70 | SLC6A4 (0.52) | SLC6A4HTR6IDO1HTR1ADRD1 | |
| SCHEMBL401146 | 0.70 | DRD2 (0.49) | SLC6A4HTR6IDO1MAP3K14HTR1A | |
| SCHEMBL91369 | 0.70 | SLC6A4 (0.49) | SLC6A4HTR6IDO1MAP3K14HTR1A | |
| SCHEMBL22359655 | 0.70 | SLC6A4 (0.49) | SLC6A4HTR6IDO1MAP3K14HTR1A | |
| SCHEMBL29994158 | 0.70 | SLC6A4 (0.52) | SLC6A4HTR6IDO1HTR1ADRD1 | |
| SCHEMBL14142175 | 0.70 | AR (0.51) | SLC6A4HTR6IDO1MAP3K14HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053536-B | Trifluoromethaneselenisation of electron-rich aromatic or heteroaromatic hydrocarbons | 武汉理工大学 | 2022-01-04 | — | — | CN | disclosed |