SCHEMBL31456338

SCHEMBL31456338

Cc1ccc(S(=O)(=O)NC(=O)N2CCCCC2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
KDM4E B2RXH2 2/20 0.67
KMT2A Q03164 2/20 0.67
TP53 P04637 1/20 0.67
GLA P06280 1/20 0.67
CYP3A4 P08684 1/20 0.67
GAA P10253 1/20 0.67
MAPT P10636 1/20 0.67
ALOX12 P18054 1/20 0.67
NFKB1 P19838 1/20 0.67
LMNA P02545 1/20 0.61
POLB P06746 1/20 0.61
KCNA1 Q09470 3/20 0.60
KCNAB1 Q14722 3/20 0.60
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
HSD17B10 Q99714 2/20 0.56
HPGD P15428 3/20 0.55
TBXA2R P21731 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tolpyrramide SCHEMBL667821 0.98 KMT2A (0.64) ALDH1A1KDM4EKMT2ATP53GLA
SCHEMBL25256003 0.84 STS (0.64) ALDH1A1KDM4EKMT2ATP53GLA
SCHEMBL14794998 0.84 POLB (0.54) ALDH1A1KMT2AGAALMNAPOLB
SCHEMBL25293555 0.81 KMT2A (0.54) ALDH1A1KDM4EKMT2ATP53GLA
Tolazamide SCHEMBL13725632 0.80 ALDH1A1 (1.00) ALDH1A1KDM4EKMT2ATP53GLA
Tolazamide SCHEMBL34417 0.80 ALDH1A1 (1.00) ALDH1A1KDM4EKMT2ATP53GLA
SCHEMBL4819602 0.80 POLB (0.53) ALDH1A1KDM4EKMT2ATP53GLA
SCHEMBL4815231 0.80 POLB (0.53) ALDH1A1KDM4EKMT2ATP53GLA
SCHEMBL25294154 0.79 KMT2A (0.51) KDM4EKMT2AMAPTLMNAPOLB
Tolazamide SCHEMBL28562527 0.79 ALDH1A1 (0.97) ALDH1A1KDM4EKMT2ATP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119530331-A Preparation method of yak oligopeptide powder product with Alzheimer disease intervention effect 天津科技大学 2025-02-28 CN disclosed