SCHEMBL28693226

SCHEMBL28693226

CCCCO[Si](O)(OCCC)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.42
TSHR P16473 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
LMNA P02545 2/20 0.37
ALDH1A1 P00352 4/20 0.36
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP19A1 P11511 1/20 0.36
TP53 P04637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PCSK9 Q8NBP7 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809355 0.93 LMNA (0.41) LTA4HTSHRTDP1L3MBTL1LMNA
SCHEMBL28218853 0.92 LTA4H (0.37) LTA4HTSHRTDP1L3MBTL1CYP1A2
SCHEMBL19809188 0.91 LTA4H (0.44) LTA4HTSHRLMNAALDH1A1CYP3A4
SCHEMBL28994572 0.88 LTA4H (0.41) LTA4HTSHRTDP1L3MBTL1CYP1A2
SCHEMBL19809253 0.87 LMNA (0.38) LTA4HTSHRLMNAALDH1A1HPGD
SCHEMBL19809442 0.86 LTA4H (0.41) LTA4HTSHRLMNAALDH1A1CYP3A4
Methane SCHEMBL28218846 0.86 LMNA (0.37) LTA4HLMNAALDH1A1HPGD
SCHEMBL19809220 0.84 LMNA (0.38) LTA4HTSHRTDP1L3MBTL1CYP1A2
Methane SCHEMBL28218856 0.83 LMNA (0.35) LMNAALDH1A1HPGD
SCHEMBL9228586 0.81 LTA4H (0.44) LTA4HTSHRTDP1L3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250754-B Silicon-containing resin composition, silicon-containing resin film, silica film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2022-01-25 CN disclosed