Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 5/20 | 0.39 |
| ▸ | DNTT | P04053 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026647 | 0.83 | BRD4 (0.46) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22279768 | 0.83 | BRD4 (0.46) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7542550 | 0.80 | NAAA (0.50) | SLC5A1NAAALMNATSHRALDH1A1 | |
| SCHEMBL7542860 | 0.80 | NAAA (0.50) | SLC5A1NAAALMNATSHRALDH1A1 | |
| Acetic Acid Methyl Ester SCHEMBL9151328 | 0.79 | BRD4 (0.42) | SLC5A1ALDH1A1KMT2ABRD4 | |
| Decane SCHEMBL8084226 | 0.77 | SLC5A1 (0.46) | SLC5A1NAAAALDH1A1 | |
| Propene SCHEMBL7744011 | 0.76 | BRD4 (0.40) | SLC5A1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL7744093 | 0.74 | PDE4A (0.37) | SLC5A1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL8262495 | 0.67 | CHRNB2 (0.43) | SLC5A1SMN1; SMN2BRD4 | |
| SCHEMBL25041425 | 0.66 | SLC5A1 (0.44) | SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113797180-A | Percutaneous absorption preparation containing donepezil as active ingredient | Icure药品株式会社 | 2021-12-17 | — | — | CN | disclosed |