SCHEMBL28695697

SCHEMBL28695697

OB(O)c1ccc(Cl)cc1-c1cccnc1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.45
CYP11B2 P19099 2/20 0.40
CYP11B1 P15538 1/20 0.37
NR4A2 P43354 1/20 0.37
FPR1 P21462 1/20 0.36
FPR2 P25090 1/20 0.36
PDE2A O00408 1/20 0.34
PDE10A Q9Y233 1/20 0.34
HTR2A P28223 2/20 0.34
PTAFR P25105 1/20 0.34
HTR2C P28335 1/20 0.34
BRD4 O60885 1/20 0.33
BRD2 P25440 1/20 0.33
BRD3 Q15059 1/20 0.33
MAPT P10636 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
CCR9 P51686 1/20 0.33
ADRA2A P08913 1/20 0.33
DRD4 P21917 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4537667 0.80 NAPRT (0.39) DHODHCYP11B2PDE10AMAPTNAPRT
SCHEMBL28679132 0.76 DHODH (0.40) DHODHNR4A2PTAFRCCR9
SCHEMBL31338563 0.76 DHODH (0.40) DHODHNR4A2PTAFRCCR9
SCHEMBL3664056 0.76 CTSD (0.44) PDE2APDE10ANPC1
SCHEMBL3106470 0.72 MAP2 (0.43) PDE2APDE10AHTR2AHTR2CNPC1
SCHEMBL28165 0.70 NAPRT (0.45) NAPRTNPC1
SCHEMBL12539016 0.70 MEN1 (0.41) RAB9A
SCHEMBL31338567 0.70 CYP11B2 (0.37) DHODHCYP11B2CYP11B1FPR1FPR2
SCHEMBL28672031 0.70 CYP11B2 (0.37) DHODHCYP11B2CYP11B1FPR1FPR2
SCHEMBL244564 0.70 IDO1 (0.42) DHODHNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943289-A Organic compound, application thereof and organic electroluminescent device 北京鼎材科技有限公司 2022-01-18 CN disclosed