Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510127 | 0.85 | KDM4E (0.69) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11956569 | 0.78 | KMT2A (0.54) | KDM4EALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL18950890 | 0.77 | KDM4E (0.47) | KDM4EGLAALDH1A1CFTRHSD17B10 | |
| SCHEMBL940016 | 0.76 | KDM4E (0.68) | KDM4EGLAALDH1A1CFTRHSD17B10 | |
| SCHEMBL20692016 | 0.76 | HSD17B10 (0.55) | KDM4EGLAALDH1A1CFTRHSD17B10 | |
| SCHEMBL18950889 | 0.76 | HSD17B10 (0.55) | KDM4EGLAALDH1A1CFTRHSD17B10 | |
| SCHEMBL2102977 | 0.75 | RAD52 (0.44) | KDM4EGLAALDH1A1KMT2APOLB | |
| SCHEMBL18474174 | 0.75 | SYK (0.53) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL2895994 | 0.75 | ALDH1A1 (0.67) | KDM4EGLAALDH1A1CFTRHSD17B10 | |
| SCHEMBL15808796 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1CFTRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874019-A | Combinations comprising benzodioxoles as GLP-1R agonists for the treatment of NASH/NAFLD and related diseases | 辉瑞大药厂 | 2021-12-31 | — | — | CN | disclosed |