SCHEMBL2895994

SCHEMBL2895994

COC(=O)c1cccc(C(=O)OC)c1N

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
HSD17B10 Q99714 3/20 0.67
CFTR P13569 1/20 0.67
TSHR P16473 2/20 0.57
LMNA P02545 1/20 0.57
KDM4E B2RXH2 5/20 0.53
ATM Q13315 2/20 0.53
POLB P06746 1/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA9 Q16790 2/20 0.53
CA5A P35218 1/20 0.53
GAA P10253 5/20 0.50
MAPT P10636 4/20 0.50
HPGD P15428 3/20 0.50
GLA P06280 2/20 0.50
KMT2A Q03164 2/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465737 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL31634613 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL14828745 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL28957307 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL27475798 0.90 ALDH1A1 (0.56) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL505249 0.90 ALDH1A1 (0.71) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL31589985 0.90 ALDH1A1 (0.71) ALDH1A1HSD17B10CFTRTSHRLMNA
Ether SCHEMBL5903649 0.89 ALDH1A1 (0.55) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL29601872 0.88 ALDH1A1 (0.58) ALDH1A1HSD17B10CFTRTSHRLMNA
SCHEMBL31038441 0.88 LMNA (0.66) ALDH1A1HSD17B10CFTRTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104549164-B Micropore metal organic framework materials adsorbed for methane and acetylene and store and preparation method thereof 浙江大学 2016-08-24 CN claimed
EP-3166981-B1 OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2026-05-13 EP disclosed
CN-119528992-A Ester-substituted palladium complex and preparation method and application thereof 链行走新材料科技(广州)有限公司 2025-02-28 CN disclosed
CN-119463134-A Application of ester-substituted palladium complex in preparation of long ether chain thiophene copolymer 链行走新材料科技(广州)有限公司 2025-02-18 CN disclosed
CN-115279730-B 2, 5-Or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group, useful as medicaments OM药物公司 2025-02-14 CN disclosed
EP-4118069-B1 PARA-HYDROQUINONE DERIVATIVES AS VEGF, TNF AND/OR IL INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATORY DISEASES OM PHARMA SA (CH) 2024-10-23 EP disclosed
US-12110307-B2 Self-immolative systems THE SECRETARY OF STATE FOR DEFENCE (GB) 2024-10-08 US disclosed
EP-3459975-B1 POLYMERIC ACID CATALYSTS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2024-10-02 EP disclosed
US-20230150951-A1 2,5- OR 2,6-DISUBSTITUTED HYDROQUINONE DERIVATIVES WITH AT LEAST ONE CARBOXY, SULFO OR AMIDO GROUP USEFUL AS MEDICAMENTS OM PHARMA SA (CH) 2023-05-18 US disclosed
US-11584805-B2 Oligosaccharide compositions and methods for producing thereof DSM NUTRITIONAL PRODUCTS, LLC (US) 2023-02-21 US disclosed
US-RE33635-E Enzymatic assay method TOYO JOZO KABUSHIKI KAISHA (JP) 1991-07-09 US disclosed
US-4931502-A Ductile, blow moldable composition containing a styrene-maleimide copolymer bearing pendant carboxyl or hydroxyl groups ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-06-05 US disclosed
EP-0357459-A2 Moldable styrene-maleic anhydride/polybutylene terephthalate composition ARCO Chemical Technology, L.P. (US) 1990-03-07 EP disclosed
US-4891405-A STYRENE-MALEIMIDE COPOLYMER HAVING PENDANT CARBOXYL OR GROUPS ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-01-02 US disclosed
US-4711898-A 4-quinolone derivatives having anti-inflammatory, anti-allergic, antitussive, expectorant and antithrombotic activity NIPPON SHINYAKU CO., LTD. (JP) 1987-12-08 US disclosed
US-4681841-A CONSUMING OXYGEN OR GENERATING A PIGMENT; MEASUREMENT BY AN OXYGEN ELECTRODE OR COLORIMETRIC ASSAY TOYO JOZO KABUSHIKI KAISHA (JP) 1987-07-21 US disclosed
EP-0104959-B1 4-QUINOLONE DERIVATIVES NIPPON SHINYAKU COMPANY, LIMITED (JP) 1987-01-21 EP disclosed
EP-0169167-A2 Process for dyeing high-molecular organic materials, and metal complexes CIBA-GEIGY AG (CH) 1986-01-22 EP disclosed
EP-0104959-A1 4-Quinolone derivatives NIPPON SHINYAKU COMPANY, LIMITED (JP) 1984-04-04 EP disclosed
US-4302241-A N-(PYRIMIDIN-2-YL-AMINOCARBONYL) ARYL SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150951-A1 2,5- OR 2,6-DISUBSTITUTED HYDROQUINONE DERIVATIVES WITH AT LEAST ONE CARBOXY, SULFO OR AMIDO GROUP USEFUL AS MEDICAMENTS HRH4, NCOA4, HRH3 ALDH1A1 3025/4885HSD17B10 115/4885CFTR 1948/4885
US-11584805-B2 Oligosaccharide compositions and methods for producing thereof OSTC, FUT5, FUT6 ALDH1A1 2641/4885HSD17B10 1297/4885CFTR 3407/4885
US-12110307-B2 Self-immolative systems MCL1, BCL3, BAP1 ALDH1A1 3669/4885HSD17B10 4342/4885CFTR 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.