SCHEMBL28696174

SCHEMBL28696174

CCOC=Cc1nccc(OC)c1OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 5/20 0.37
TUBB4A P04350 4/20 0.37
TUBB P07437 4/20 0.37
TUBA3C P0DPH7 4/20 0.37
TUBA1B P68363 4/20 0.37
TUBA4A P68366 4/20 0.37
TUBB4B P68371 4/20 0.37
TUBB3 Q13509 4/20 0.37
TUBB2A Q13885 4/20 0.37
TUBB8 Q3ZCM7 4/20 0.37
TUBA3E Q6PEY2 4/20 0.37
TUBA1A Q71U36 4/20 0.37
TUBA1C Q9BQE3 4/20 0.37
TUBB6 Q9BUF5 4/20 0.37
TUBB2B Q9BVA1 4/20 0.37
MAPT P10636 4/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25806076 1.00 TUBB1 (0.37) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5765086 0.79 NFE2L2 (0.51) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL4111524 0.73 ALDH1A1 (0.37) TUBB1MAPTALDH1A1KDM4ECYP1A1
SCHEMBL30963127 0.73 ALDH1A1 (0.37) TUBB1MAPTALDH1A1KDM4ECYP1A1
SCHEMBL7823013 0.72 KDM4E (0.51) ALDH1A1KDM4ECYP1A1CYP1A2CYP2D6
SCHEMBL7823012 0.72 KDM4E (0.51) ALDH1A1KDM4ECYP1A1CYP1A2CYP2D6
SCHEMBL9681820 0.71 CA12 (0.41) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9681809 0.71 CA12 (0.41) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL458517 0.68 ALDH1A1 (0.41) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL3312005 0.68 ALDH1A1 (0.41) MAPTALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213424-B Synthesis method of furan [3,2-b ] pyridine derivative 杭州高光制药有限公司 2023-05-26 CN disclosed
CN-114213424-A Synthetic method of furan [3, 2-b ] pyridine derivative 杭州澳赛诺生物科技有限公司 2022-03-22 CN disclosed