Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696174 | 0.79 | TUBB1 (0.37) | NFE2L2SYKMEN1KMT2ALMNA | |
| SCHEMBL25806076 | 0.79 | TUBB1 (0.37) | NFE2L2SYKMEN1KMT2ALMNA | |
| SCHEMBL8554208 | 0.79 | NFE2L2 (0.51) | NFE2L2PLAUSYKPDGFRBPDGFRA | |
| SCHEMBL9000315 | 0.78 | NFE2L2 (0.58) | NFE2L2PLAUPDGFRBPDGFRANPC1 | |
| SCHEMBL14727114 | 0.75 | FDPS (0.52) | NFE2L2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5641184 | 0.73 | NFE2L2 (0.53) | NFE2L2PLAUSYKPDGFRBPDGFRA | |
| SCHEMBL33532515 | 0.72 | NFE2L2 (0.52) | NFE2L2PLAUPDGFRBPDGFRANPC1 | |
| SCHEMBL2084338 | 0.72 | NFE2L2 (0.55) | NFE2L2PLAUPDGFRBPDGFRANPC1 | |
| SCHEMBL4082035 | 0.72 | NFE2L2 (0.51) | NFE2L2PLAUPDGFRBPDGFRANPC1 | |
| SCHEMBL4378934 | 0.72 | NFE2L2 (0.51) | NFE2L2PLAUPDGFRBPDGFRANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658285-A1 | COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE | ELI LILLY AND COMPANY (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005019212-A1 | COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |