Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040702 | 0.87 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPK1MAPTATM | |
| SCHEMBL8198831 | 0.81 | KDM4E (0.64) | TARBP2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL18017492 | 0.80 | CA12 (0.60) | ALDH1A1LMNAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL10379236 | 0.79 | L3MBTL1 (0.83) | ALDH1A1LMNAMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL16974078 | 0.78 | ALDH1A1 (0.48) | TARBP2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL11402662 | 0.77 | TRPM8 (0.47) | TARBP2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL20313136 | 0.77 | TSHR (0.53) | ALDH1A1LMNAMAPK1MAPTATM | |
| SCHEMBL16351849 | 0.77 | TSHR (0.56) | TARBP2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL16351839 | 0.77 | TSHR (0.56) | TARBP2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL7328943 | 0.75 | TSHR (0.50) | TARBP2ALDH1A1LMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105864-A | Method for synthesizing symmetrical 2,3,5, 6-tetra-substituted pyridine | 温州医科大学 | 2022-03-01 | — | — | CN | disclosed |