Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391801 | 0.87 | HSD11B1 (0.51) | HSD11B1MEN1KMT2AJAK2JAK1 | |
| SCHEMBL5367694 | 0.86 | OPRM1 (0.54) | HSD11B1OPRM1 | |
| SCHEMBL14410252 | 0.86 | HSD11B1 (0.43) | HSD11B1CCR5NR1H4SLC6A2SLC6A4 | |
| SCHEMBL28691449 | 0.83 | HSD11B1 (0.47) | HSD11B1MEN1KMT2A | |
| SCHEMBL14417237 | 0.83 | SLC6A4 (0.50) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17560075 | 0.78 | LIPE (0.41) | MEN1KMT2AUSP30GPR119 | |
| SCHEMBL18154352 | 0.76 | HSD11B1 (0.48) | HSD11B1MEN1KMT2AJAK2JAK1 | |
| SCHEMBL7425320 | 0.76 | KDM4E (0.38) | HSD11B1GPR119KDM4ECYP2D6SLC6A2 | |
| SCHEMBL5500431 | 0.75 | HSD11B1 (0.39) | HSD11B1MEN1KMT2AJAK2JAK1 | |
| SCHEMBL18585599 | 0.75 | HSD11B1 (0.44) | HSD11B1JAK2JAK1CCR5NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-113227068-A | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2021-08-06 | — | — | CN | disclosed |