Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.57 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.57 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.57 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.57 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848691 | 0.89 | TRPV6 (0.63) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL28610015 | 0.77 | TRPV6 (0.56) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL263598 | 0.76 | TRPV6 (0.52) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL28718291 | 0.76 | TRPV6 (0.52) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL9362337 | 0.74 | ENPP2 (0.50) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL184420 | 0.74 | TRPV6 (0.50) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL7908605 | 0.74 | TRPV6 (0.50) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL244920 | 0.74 | TRPV6 (0.50) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL56106 | 0.74 | TRPV6 (0.50) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL1845171 | 0.74 | TRPV6 (0.50) | TRPV6ORAI1ORAI2ORAI3PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113956295-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-01-21 | — | — | CN | disclosed |