SCHEMBL184420

SCHEMBL184420

OB(OF)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 4/20 0.50
ORAI1 Q96D31 3/20 0.50
ORAI2 Q96SN7 3/20 0.50
ORAI3 Q9BRQ5 3/20 0.50
ENPP2 Q13822 3/20 0.50
PCSK9 Q8NBP7 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
CA1 P00915 4/20 0.38
MGLL Q99685 3/20 0.38
CA2 P00918 3/20 0.38
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
TRPM2 O94759 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28736866 0.87 TRPV6 (0.39) TRPV6ORAI1ORAI2ORAI3ENPP2
SCHEMBL28112576 0.83 CA1 (0.64) CA1CA2TSHR
SCHEMBL1848691 0.78 TRPV6 (0.63) TRPV6ORAI1ORAI2ORAI3ENPP2
SCHEMBL27996709 0.77 ENPP2 (0.52) TRPV6ORAI1ORAI2ORAI3ENPP2
SCHEMBL6522357 0.77 CA1 (0.61) ENPP2CA7CA14CA1CA2
SCHEMBL28718291 0.76 TRPV6 (0.52) TRPV6ORAI1ORAI2ORAI3ENPP2
SCHEMBL263598 0.76 TRPV6 (0.52) TRPV6ORAI1ORAI2ORAI3ENPP2
SCHEMBL1849399 0.75 ORAI1 (0.32) TRPV6ORAI1ORAI2ORAI3
SCHEMBL1485477 0.75 USP2 (0.34) MEN1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL27965000 0.75 CA2 (0.54) TRPV6ORAI1ORAI2ORAI3ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12188898-B2 Non-enzymatic electrochemical sensor for measuring analytes TERUMO KABUSHIKI KAISHA (JP) 2025-01-07 US claimed
CN-111629746-B Charge switchable polymer depot for glucose-triggered insulin delivery with ultra-fast response 北卡罗来纳州立大学 2024-04-16 CN claimed
US-20240108253-A1 COLLOIDAL CRYSTAL MICRONEEDLE PATCH FOR GLUCOSE MONITORING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-04 US claimed
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2024-01-18 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-11813352-B2 Charge-switchable polymeric depot for glucose-triggered insulin delivery with ultrafast response NORTH CAROLINA STATE UNIVERSITY (US) 2023-11-14 US claimed
CN-115746196-A Preparation method and application of isopropyl methacrylamide-fluorophenylboronic acid copolymerized glucose response microgel 电子科技大学长三角研究院(湖州) 2023-03-07 CN claimed
CN-115715756-A Acryloyl glycinamide-fluorine-containing phenylboronic acid group sugar-sensitive microneedle and preparation method thereof 浙江大学 2023-02-28 CN claimed
CN-114956924-A Method for synthesizing polyfluoro biaryl through series/coupling reaction 河南科技学院 2022-08-30 CN claimed
WO-2022159486-A1 COLLOIDAL CRYSTAL MICRONEEDLE PATCH FOR GLUCOSE MONITORING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-07-28 WO claimed
US-20200360269-A1 CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE NORTH CAROLINA STATE UNIVERSITY 2020-11-19 US claimed
CN-107849080-B Catalyst comprising a metallocene complex and a cocatalyst SABIC环球技术有限责任公司 2020-10-30 CN claimed
EP-3713594-A1 CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE North Carolina State University (US) 2020-09-30 EP claimed
CN-111629746-A Charge switchable polymer depot for glucose triggered insulin delivery with ultra-fast response 北卡罗来纳州立大学 2020-09-04 CN claimed
WO-2019104006-A1 CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE NORTH CAROLINA STATE UNIVERSITY (US) 2019-05-31 WO claimed
EP-3134419-B1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO CORP (JP) 2019-03-13 EP claimed
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2017-08-03 US claimed
EP-3134419-A2 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES Glucovation, Inc. (US) 2017-03-01 EP claimed
WO-2015164578-A9 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES GLUCOVATION, INC. (US) 2016-02-18 WO claimed
WO-2015164578-A2 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES GLUCOVATION, INC. (US) 2015-10-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES SPR, SRR, BLVRB TRPV6 2806/4885ORAI1 2446/4885ORAI2 2680/4885
US-12188898-B2 Non-enzymatic electrochemical sensor for measuring analytes SPR, SRR, BLVRB TRPV6 2806/4885ORAI1 2446/4885ORAI2 2680/4885
US-11813352-B2 Charge-switchable polymeric depot for glucose-triggered insulin delivery with ultrafast response IAPP, GPR119, INSR TRPV6 3652/4885ORAI1 883/4885ORAI2 4303/4885
US-20200360269-A1 CHARGE-SWITCHABLE POLYMERIC DEPOT FOR GLUCOSE-TRIGGERED INSULIN DELIVERY WITH ULTRAFAST RESPONSE IAPP, GPR119, INSR TRPV6 3652/4885ORAI1 883/4885ORAI2 4303/4885
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES SPR, BLVRB, XDH TRPV6 3098/4885ORAI1 2207/4885ORAI2 2491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.