SCHEMBL28696551

SCHEMBL28696551

CC(C)[C@H](N)C(=O)N(O)C(=O)Nc1ncnc2[nH]cnc12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.30
▸ BRAF P15056 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28688018 0.82 — —
SCHEMBL29184339 0.77 SPHK1 (0.36) BRD4BRAFSMN1; SMN2
SCHEMBL19699540 0.74 GSK3B (0.38) BRD4BRAFSMN1; SMN2
SCHEMBL9621683 0.74 MAOA (0.40) BRD4BRAFSMN1; SMN2
SCHEMBL17372558 0.72 NPC1 (0.35) BRAFSMN1; SMN2
SCHEMBL17372562 0.72 NPC1 (0.35) BRAFSMN1; SMN2
SCHEMBL536914 0.72 BRAF (0.47) BRD4BRAFSMN1; SMN2
SCHEMBL5437606 0.71 MKNK1 (0.38) BRD4BRAFSMN1; SMN2
SCHEMBL22118770 0.71 BRD4 (0.40) BRD4BRAFSMN1; SMN2
SCHEMBL29654971 0.71 BRD4 (0.40) BRD4BRAFSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118697900-A Method for preparing lipid nanoparticles 摩登纳特斯有限公司 2024-09-27 — — CN disclosed
CN-118076741-A Modified mRNA, modified non-coding RNA and uses thereof 布罗德研究所股份有限公司 2024-05-24 — — CN disclosed
CN-117159492-A Lipid nanoparticle containing sialic acid lipid derivative and application thereof 广州制高点医药科技有限公司 2023-12-05 — — CN disclosed
CN-113939282-A Method for preparing lipid nanoparticles 摩登纳特斯有限公司 2022-01-14 — — CN disclosed
CN-113710353-A Vortex mixer and related methods, systems, and apparatus 摩登纳特斯有限公司 2021-11-26 — — CN disclosed
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