Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778780 | 0.81 | XDH (0.42) | RAB9ATSHRHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL28965190 | 0.79 | XDH (0.40) | RAB9ATSHRHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL9621685 | 0.79 | SMN1; SMN2 (0.55) | RAB9ATSHRHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL536914 | 0.79 | BRAF (0.47) | RAB9ATSHRHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL13632472 | 0.78 | ABL1 (0.40) | RAB9ATSHRHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL14704317 | 0.77 | TP53 (0.46) | RAB9ATSHRHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL5437606 | 0.77 | MKNK1 (0.38) | RAB9ASMN1; SMN2NPC1XDHBRD4 | |
| SCHEMBL22118770 | 0.77 | BRD4 (0.40) | RAB9ATSHRHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL29654971 | 0.77 | BRD4 (0.40) | RAB9ATSHRHSD17B10SMN1; SMN2TP53 | |
| SCHEMBL12145167 | 0.76 | L3MBTL1 (0.39) | TSHRHSD17B10TP53XDHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186454-B1 | 6-PURINYL N-(2-CHLOROETHYL) CARBAMATE AND THIOCARBAMATE, A PROCESS FOR THEIR PREPARATION AND USE THEREOF | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1992-04-08 | — | — | EP | disclosed |
| EP-0186454-A2 | 6-Purinyl N-(2-chloroethyl) carbamate and thiocarbamate, a process for their preparation and use thereof | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1986-07-02 | — | — | EP | disclosed |