⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696551 | 0.82 | BRD4 (0.30) | — | |
| SCHEMBL29278769 | 0.80 | SPHK1 (0.32) | — | |
| SCHEMBL17372419 | 0.76 | CYP1A2 (0.30) | — | |
| SCHEMBL17372415 | 0.76 | CYP1A2 (0.30) | — | |
| SCHEMBL25244196 | 0.74 | CYP1A2 (0.31) | — | |
| SCHEMBL28960558 | 0.73 | CYP1A2 (0.41) | — | |
| SCHEMBL28960555 | 0.72 | MEN1 (0.38) | — | |
| SCHEMBL28376089 | 0.70 | ADORA3 (0.50) | — | |
| SCHEMBL17372406 | 0.69 | CYP1A2 (0.49) | — | |
| SCHEMBL29124870 | 0.69 | SYK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118697900-A | Method for preparing lipid nanoparticles | 摩登纳特斯有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118076741-A | Modified mRNA, modified non-coding RNA and uses thereof | 布罗德研究所股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117159492-A | Lipid nanoparticle containing sialic acid lipid derivative and application thereof | 广州制高点医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-113939282-A | Method for preparing lipid nanoparticles | 摩登纳特斯有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-113710353-A | Vortex mixer and related methods, systems, and apparatus | 摩登纳特斯有限公司 | 2021-11-26 | — | — | CN | disclosed |