Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28711726 | 0.84 | KIF11 (0.38) | KIF11ALDH1A1TRPV1SLC6A2P2RY14 | |
| SCHEMBL25228674 | 0.79 | KIF11 (0.52) | KIF11SLC6A2P2RY14PIK3CAESR1 | |
| SCHEMBL28696774 | 0.78 | ABCG2 (0.43) | ALDH1A1MEN1GAAMAPTKMT2A | |
| SCHEMBL30307086 | 0.78 | HSD17B1 (0.40) | KIF11TNKSPARP1TNKS2ALDH1A1 | |
| SCHEMBL24604991 | 0.72 | KIF11 (0.40) | KIF11TNKSPARP1TNKS2ALDH1A1 | |
| SCHEMBL14191585 | 0.71 | KIF11 (0.44) | KIF11TNKSTNKS2ALDH1A1MEN1 | |
| SCHEMBL25227071 | 0.71 | KIF11 (0.43) | KIF11SLC6A2P2RY14PIK3CAESR1 | |
| SCHEMBL4440788 | 0.70 | KIF11 (0.42) | KIF11PARP1ALDH1A1MEN1GAA | |
| SCHEMBL24604987 | 0.70 | ESR1 (0.44) | KIF11TNKSPARP1TNKS2ALDH1A1 | |
| SCHEMBL12197224 | 0.69 | HPRT1 (0.42) | KIF11TNKSTNKS2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149307-B | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-114149307-A | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2022-03-08 | — | — | CN | disclosed |