Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28935252 | 0.85 | ABCG2 (0.41) | ABCG2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL25436806 | 0.84 | MEN1 (0.43) | MAOBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30554744 | 0.80 | NTRK1 (0.38) | ABCG2MAOBMEN1KMT2AMAPT | |
| SCHEMBL29227272 | 0.80 | NTRK1 (0.38) | ABCG2MAOBMEN1KMT2AMAPT | |
| SCHEMBL28713191 | 0.80 | ADORA3 (0.37) | ABCG2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL13145980 | 0.79 | CA1 (0.44) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25226274 | 0.79 | ESR2 (0.52) | MAOBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28696753 | 0.78 | KIF11 (0.37) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL30307098 | 0.78 | NTRK1 (0.47) | ABCG2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL29227271 | 0.76 | ABCG2 (0.39) | ABCG2MAOBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149307-B | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-114149307-A | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2022-03-08 | — | — | CN | disclosed |