SCHEMBL28696952

SCHEMBL28696952

O=C1C=CC(O)OC1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.39
MAPT P10636 4/20 0.39
POLB P06746 1/20 0.39
ALDH1A1 P00352 6/20 0.38
CA2 P00918 2/20 0.38
KMT2A Q03164 5/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RAB9A P51151 1/20 0.36
SLC6A3 Q01959 1/20 0.36
EPHX1 P07099 1/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 2/20 0.33
MAPK1 P28482 2/20 0.33
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28684501 0.82 ALDH1A1 (0.41) MAPTALDH1A1CA2KMT2ASMN1; SMN2
SCHEMBL9707918 0.82 ALDH1A1 (0.38) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL6231295 0.79 ALDH1A1 (0.39) KDM4EMAPTPOLBALDH1A1CA2
SCHEMBL10570948 0.73 TSHR (0.40) KDM4EMAPTPOLBALDH1A1KMT2A
SCHEMBL10571447 0.71 CYP2D6 (0.36) MAPTPOLBKMT2ASMN1; SMN2SLC6A3
SCHEMBL7252825 0.68 ALDH1A1 (0.42) KDM4EMAPTPOLBALDH1A1CA2
SCHEMBL24515872 0.67 EDNRA (0.39) MAPTPOLBALDH1A1CA2SMN1; SMN2
SCHEMBL10745108 0.67 EDNRA (0.39) MAPTPOLBALDH1A1CA2SMN1; SMN2
SCHEMBL18937978 0.66
SCHEMBL5742781 0.64 ALDH1A1 (0.39) KDM4EMAPTPOLBALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521281-B Method for preparing pyrone compound by photocatalytic furfuryl alcohol 西南林业大学 2024-06-04 CN disclosed
CN-114133367-B Preparation method of sulfoxide imido dihydropyrone derivative 大连理工常熟研究院有限公司 2023-03-21 CN disclosed
CN-115521281-A Method for preparing pyrone compound by photocatalytic furfuryl alcohol 西南林业大学 2022-12-27 CN disclosed
CN-114133367-A Preparation method of sulphoxide imino dihydropyrone derivatives 大连理工常熟研究院有限公司 2022-03-04 CN disclosed