Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231295 | 0.69 | ALDH1A1 (0.39) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL5742781 | 0.69 | ALDH1A1 (0.39) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL21703526 | 0.69 | ALDH1A1 (0.43) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL28890875 | 0.69 | CA2 (0.47) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL31650964 | 0.69 | ALDH1A1 (0.56) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL28696952 | 0.68 | KDM4E (0.39) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL30725794 | 0.67 | CYP1A2 (0.30) | ALDH1A1CA2CYP1A2 | |
| SCHEMBL28452557 | 0.67 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL983728 | 0.67 | ALDH1A1 (0.54) | ALDH1A1CA2RAB9ASLC6A3MAPT | |
| SCHEMBL6661925 | 0.65 | TLR9 (0.41) | HTTTSHRCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818660-B | Beta-hydroxylase inhibitors for the treatment of cancer | 罗得岛医院 | 2023-09-12 | — | — | CN | disclosed |
| US-20180080061-A1 | BIOSYNTHETIC LABELING AND SEPARATION OF RNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-03-22 | — | — | US | disclosed |
| WO-2003018575-A1 | 5-SUBSTITUTED-3(2H)-FURANONES USEFUL FOR INHIBITION OF FARNESYL-PROTEIN TRANSFERASE | WYETH HOLDINGS CORPORATION (US) | 2003-03-06 | — | — | WO | disclosed |