Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.52 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178001 | 0.88 | CA1 (0.58) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL3637063 | 0.87 | LMNA (0.68) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL28704869 | 0.85 | LMNA (0.59) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL28706333 | 0.85 | FLT1 (0.59) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL28684587 | 0.84 | LMNA (0.54) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL28691429 | 0.81 | PTGES (0.53) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL27901373 | 0.80 | LMNA (0.53) | CA1CA2CA9LMNAKAT6A | |
| SCHEMBL28698402 | 0.78 | FLT1 (0.58) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL9176062 | 0.78 | LMNA (0.57) | CA1CA2CA9LMNAALKBH2 | |
| SCHEMBL9176782 | 0.78 | FLT1 (0.63) | CA1CA2CA9LMNAALKBH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114059090-A | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2022-02-18 | — | — | CN | disclosed |