Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.60 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.60 |
| ▸ | ITGAV | P06756 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178001 | 0.90 | CA1 (0.58) | LMNAALKBH2ALKBH3ITGAVCA1 | |
| SCHEMBL9180237 | 0.87 | LMNA (0.58) | LMNAALKBH2ALKBH3ITGAVCA1 | |
| SCHEMBL28697103 | 0.87 | CA1 (0.55) | LMNAALKBH2ALKBH3ITGAVCA1 | |
| SCHEMBL28706333 | 0.87 | FLT1 (0.59) | LMNAALKBH2ALKBH3ITGAVCA1 | |
| SCHEMBL9176062 | 0.86 | LMNA (0.57) | LMNAALKBH2ALKBH3CA1CA9 | |
| SCHEMBL3206422 | 0.85 | SLC1A3 (0.55) | LMNAALKBH2ALKBH3ITGAVCA1 | |
| SCHEMBL28704869 | 0.85 | LMNA (0.59) | LMNAALKBH2ALKBH3ITGAVCA1 | |
| SCHEMBL28691429 | 0.84 | PTGES (0.53) | LMNAALKBH2ALKBH3ITGAVCA1 | |
| SCHEMBL29551608 | 0.84 | PTGS2 (0.66) | LMNAALKBH2ALKBH3KMT2APOLB | |
| SCHEMBL9301023 | 0.84 | LMNA (0.54) | LMNAALKBH2ALKBH3ITGAVCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399732-B1 | Benzimidazole derivatives | ZENECA LTD (GB) | 1995-07-26 | — | — | EP | claimed |
| EP-0542556-B1 | Thermosensitive recording material | NEW OJI PAPER CO LTD (JP) | 1995-07-19 | — | — | EP | claimed |
| US-5314859-A | Thermosensitive recording material | OJI PAPER CO., LTD. (JP) | 1994-05-24 | — | — | US | claimed |
| EP-0542556-A1 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0399732-A1 | Benzimidazole derivatives | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | claimed |
| CN-114059090-B | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114059090-A | Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative | 福州大学 | 2022-02-18 | — | — | CN | disclosed |
| EP-2170825-A2 | SUBSTITUTED INDOLES | Auspex Pharmaceuticals, Inc. (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009018280-A2 | SUBSTITUTED INDOLES | AUSPEX PHARAMACEUTICALS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| US-7074388-B2 | Water stabilized medicinal aerosol formulation | KOS LIFE SCIENCE, INC. (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1569617-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | Kos Life Sciences, Inc. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004022035-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | KOS PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
| EP-0489548-B1 | A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | disclosed |
| US-5314859-A | Thermosensitive recording material | OJI PAPER CO., LTD. (JP) | 1994-05-24 | — | — | US | disclosed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0542556-A1 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |
| EP-0503856-A1 | Thermosensitive recording material | OJI PAPER COMPANY LIMITED (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0489548-A1 | A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof | ZENECA LIMITED (GB) | 1992-06-10 | — | — | EP | disclosed |
| EP-0453210-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |