Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887729 | 0.74 | ALDH1A1 (0.44) | CRBNKDM4ECA2PTGS1MMP12 | |
| SCHEMBL30589152 | 0.67 | — | — | |
| SCHEMBL13899973 | 0.65 | — | — | |
| SCHEMBL11247871 | 0.65 | CA2 (0.35) | CRBNKDM4ECA2PTGS1MMP12 | |
| SCHEMBL8225875 | 0.65 | — | — | |
| SCHEMBL28693479 | 0.65 | CRBN (0.31) | CRBNKDM4ECA2PTGS1MMP12 | |
| SCHEMBL4445189 | 0.64 | USP2 (0.54) | KDM4ECA2USP2TSHRALDH1A1 | |
| SCHEMBL28826281 | 0.63 | — | — | |
| SCHEMBL21816739 | 0.63 | — | — | |
| SCHEMBL28243453 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880866-B | Aza-tetrahydronaphthyridine compound, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113880866-A | Aza-tetrahydronaphthyridine compound, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-01-04 | — | — | CN | disclosed |