Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698477 | 0.85 | BACE1 (0.47) | ABCB1SIGMAR1L3MBTL1MAPT | |
| SCHEMBL29576850 | 0.82 | ABCB1 (0.42) | ABCB1CHRM4RORCMAPT | |
| SCHEMBL21457808 | 0.82 | ABCB1 (0.42) | ABCB1CHRM4RORCMAPT | |
| SCHEMBL29707321 | 0.79 | ABCB1 (0.39) | ABCB1CHRM4L3MBTL1RORCMAPT | |
| SCHEMBL19212145 | 0.78 | GRM5 (0.45) | L3MBTL1MAPT | |
| SCHEMBL28673972 | 0.77 | LMNA (0.46) | L3MBTL1MAPT | |
| SCHEMBL29707383 | 0.76 | MAPT (0.38) | ABCB1CHRM4RORCMAPT | |
| SCHEMBL28931799 | 0.76 | NR1H2 (0.51) | ABCB1NR1H2NR1H3TMEM97SIGMAR1 | |
| SCHEMBL28683499 | 0.75 | BACE1 (0.47) | L3MBTL1MAPT | |
| SCHEMBL19212126 | 0.75 | LMNA (0.40) | CHRM4L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |